منابع مشابه
Increased plasma colloid osmotic pressure facilitates the uptake of therapeutic macromolecules in a xenograft tumor model.
Elevated tumor interstitial fluid pressure (TIFP) is a characteristic of most solid tumors. Clinically, TIFP may hamper the uptake of chemotherapeutic drugs into the tumor tissue reducing their therapeutic efficacy. In this study, a means of modulating TIFP to increase the flux of macromolecules into tumor tissue is presented, which is based on the rationale that elevated plasma colloid osmotic...
متن کاملStudies on the Regulation of Osmotic Pressure
1. In pure gelatin solutions the conductivity of the solution increases with increasing concentrations, regardless of the hydrogen ion concentration. The actual value of the specific conductivity is greater at that reaction where the degree of ionization is greater. 2. The addition of gelatin in increasing concentrations to a 0.6 per cent sodium chloride solution affects the conductivity of tha...
متن کاملCALCULATION OF OSMOTIC PRESSURE USING A CLOSED SYSTEM MODEL
In this work we have used a closed system model to derive an analytical equation for the osmotic pressure of two component electrolyte and non-electrolyte solutions. In order to do so, we have used an equation of state, known as the dense system equation of state (DSEOS), for the model system. Based on the model, a new definition is given for the osmotic pressure of a closed system. Good ag...
متن کاملPolysaccharides and other Macromolecules 4. THE OSMOTIC PRESSURE OF MIXTURES OF SERUM ALBUMIN AND HYALURONIC ACID* BY T. C. LAURENT
Ogston & Phelps (1961) found that hyaluronic acid markedly affects the partition of diffusible macromolecules between solutions of the polysaccharide and buffer. The authors explain the phenomenon as a steric exclusion of macromolecular solutes from solutions containing randomly coiled hyaluronic acid chains. From these results one can expect that hyaluronic acid and similar substances would ex...
متن کاملEffects of Charge on Osmotic Reflection Coefficients of Macromolecules in Fibrous Membranes
A model based on continuum hydrodynamics and electrostatics was developed to predict the combined effects of molecular charge and size on the osmotic reflection coefficient (so) of a macromolecule in a fibrous membrane, such as a biological hydrogel. The macromolecule was represented as a sphere with a constant surface charge density, and the membrane was assumed to consist of an array of paral...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Acta Chemica Scandinavica
سال: 1960
ISSN: 0904-213X
DOI: 10.3891/acta.chem.scand.14-1185